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ASK Study Update - December 2010

The ASK Study is an Australian-based, world first familial study into Sarcoma cancer. Rainbows for Kate has dedicated the majority of its funding to this study, as research is the one thing we are certain can make a difference to the understanding, treatment and eventual cure for Sarcoma cancer. In less than 12 months since it began, the ASK Study has far exceeded the expectations of everyone involved in it, including the Doctors from the Australian Sarcoma Study Group (ASSG) who are coordinating and running the study.

Results from the Study so far are supporting the hypothesis that there is an underlying genetic component to adult-onset Sarcoma. Doctors have identified new patterns of cancers and increased family incidence of Hodgkin's lymphoma, gastric, brain and breast cancers. None of this was previously known. They are also finding a higher than expected mutation rate in Sarcoma cases of the important 'p53' gene, and that these cancers are occurring around 10 years earlier than in the general population.

The ASK Study now has more than 250 families participating from across Victoria, Queensland, NSW and SA, with a new site opening in WA this month. For each participant the Study collects family history, history of Sarcoma-specific risk factors and also blood samples. This familial information is what will form the basis of the Sarcoma cancer genetics database, a clinical resource for scientists to better understand the genetic basis of Sarcoma and the development of treatments.

There has also been significant interest to join the ASK study from international hospitals in India, France, the UK, several places in Europe and the US. As these hospitals get approval and join the study the magnitude of the ASK Study and its findings will increase significantly.

Thank you for your ongoing support,

Rainbows for Kate Foundation
20 December 2010


On Tuesday the 21st of July 2009, the Rainbows for Kate Australian Sarcoma Kindred Study was officially launched at the RPA Hospital in Sydney. Patients and families of those that have suffered Sarcoma cancer can now participate in a family-based study that is endeavouring to decipher genetic significance in Sarcoma cancer. This is a world-first study and we are very proud that the study is now offically live.
For more information please see the link below:

We look forward to reporting on the progress of this study as it comes to hand.

Rainbows for Kate Foundation
23 July 2009


From the hundreds of generous donations Rainbows for Kate has received so far, we are delighted to inform you that to date have raised over $500,000 dollars !

This is an incredible achievement and we are extremely proud of the support we have received from our ever-expanding network of friends. Importantly, it is time to provide an update on where we are with respect to putting this money to good use.

In consultation with Dr David Thomas at the Peter McCallum Cancer Research Institute in Melbourne, we are in the process of commissioning a liquid nitrogen container and a -70°C freezer for the purpose of containing the data necessary for meaningful research into Sarcoma cancers to begin. This is an extremely exciting development, as it is the very first time this will have been done in Australia and it has only been made possible because of your support. As well as the nitrogen container and freezer, we are also establishing plans to employ dedicated research nurses and database support staff to assist in the collection and management of the data we collect.

The Rainbows for Kate Foundation is also looking ahead, and we are planning to apply for Cancer Australia funding in late 2009 / early 2010. Again this is only possible because of the groundswell of support Rainbows for Kate has received. In the meantime, we look forward to your ongoing support and, most importantly, we look forward to providing you with further updates on our collective fight against cancer.

Thank you all so much,

Rainbows for Kate
19 May 2009

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